Articles from Faeth Therapeutics

Faeth Therapeutics, a clinical-stage biotechnology company integrating precision nutrition with combination therapies to address cancer metabolism, today announced publication of a preclinical proof-of-concept study supporting its rationale for targeting cancer metabolism through multi-node inhibition, including both therapeutics and an insulin-suppressing diet. The findings, published today in the peer-reviewed British Journal of Cancer, show that the three-pronged PIKTOR approach – using Faeth’s dual PI3K/AKT/mTOR pathway inhibitors FTH-001 (serabelisib) and FTH-003 (sapanisertib) along with dietary modification, added to paclitaxel – demonstrated tumor regression in endometrial and breast cancer models. In March, Faeth launched a Phase 2 trial with The GOG Foundation using this PIKTOR strategy in patients with endometrial cancer, the cancer most strongly linked to obesity and metabolic syndrome.

Faeth Therapeutics (Faeth), a clinical-stage biotechnology company focused on metabolism, and The GOG Foundation, Inc. (GOG-F), a not-for-profit organization with the purpose of promoting excellence in the quality and integrity of clinical and translational scientific research in the field of gynecologic malignancies, today announced the first patient has been dosed in its Phase 2 combination trial of PIKTOR, which is FTH-001 (serabelisib) and FTH-003 (sapanisertib) with paclitaxel. The trial is the most advanced of its kind to investigate a novel approach of dual PI3Kɑ-mTORC1/2 inhibition targeting cancer metabolism in patients with endometrial cancer.

Faeth Therapeutics (Faeth), a clinical biotechnology company focused on rethinking the science of cancer using metabolism, announced the appointment of Dr. Stephen Hahn, former FDA Commissioner and oncology expert, and Dr. Jayson Dallas, accomplished biotech leader and former CEO of Aimmune Therapeutics, to its Board of Directors. With these strategic additions, Faeth strengthens its leadership team as it advances its metabolic oncology therapies designed to improve cancer outcomes.

Faeth Therapeutics (Faeth), a clinical-stage biotechnology company, announced that Oliver Maddocks, Co-Founder and Chief Scientific Officer, and Debbie Chirnomas, M.D., Chief Medical Officer, will present today at the Raymond James Biotech Private Company Showcase. Oliver and Debbie will discuss Faeth’s lead PIKTOR program development plans and participate in a Q&A following the presentation.

Faeth Therapeutics, (Faeth) a clinical-stage biotechnology company, announced today that Anand Parikh, Chief Executive Officer (CEO), will participate in one-on-one investor meetings at the upcoming Jefferies Global Healthcare Conference being held June 4-6 in New York.

Faeth Therapeutics, an oncology company with clinical programs combining therapeutics with metabolic optimization to achieve greater efficacy, today announced that the company will be participating in a company presentation and 1x1 investor meetings at the Stifel 2023 Healthcare Conference, taking place from November 14-15 in New York City.

Faeth Therapeutics, a leader in metabolic oncology research and treatment innovation, proudly announces the induction of its co-founder, Dr. Siddhartha Mukherjee, Assistant Professor at Columbia, Pulitzer Prize Winner, and one of Time 100's Most Influential People, into the esteemed National Academy of Medicine (NAM).

Faeth Therapeutics, a clinical-stage biotechnology company targeting cancer metabolism, today announced the appointment of Debbie Chirnomas M.D., M.P.H., as Chief Medical Officer. Dr. Chirnomas will head up the early and late-stage clinical development for Faeth’s oncology pipeline.

Faeth Therapeutics, a healthcare company developing machine learning-driven precision nutrition solutions and therapeutic regimens to treat cancer, today announced the expansion of its executive leadership team with the appointments of Thomas Strack, M.D., as Chief Medical Officer and Virginia Casadas as VP, Head of Clinical Operations.

Faeth Therapeutics, a healthcare company developing machine learning-driven precision nutrition solutions and treatment regimens to enhance cancer therapy, today announced the closing of a $20M seed financing round co-led by Khosla Ventures and Future Ventures, with participation from S2G Ventures, Digitalis, KdT Ventures, Agfunder, Cantos and Unshackled.